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extraction process, fractionation and biogenic isolation of antioxidant substances present in olefiic moringa leaves
专利权人:
UNIVERSIDADE TECNOLOGICA FEDERAL DO PARANA
发明人:
MARIÉLI KARLING,NATHALIE MERLIN,SEVERINO MATIAS DE ALENCAR,TATIANE LUIZA CADORIN OLDONI
申请号:
BR102018014571
公开号:
BR102018014571A2
申请日:
2018.07.17
申请国别(地区):
BR
年份:
2020
代理人:
摘要:
process of extraction, fractionation and bioguied isolation of antioxidant substances present in oil-spined moringa leaves refers to the process of extracting, purifying and bio-isolating substances with high antioxidant potential present in the leaves of m. oleifera, consisting of the stages of: a. Obtaining hydro-alcohol extract (e1-e5);b. fractionation of the hydro-alcohol extract obtained (e6-e9);c. purification in gel silica (e10) e16);d. isolation and identification of active compounds (e17-e20);e. Monitoring of chromatographic profile (e21-e23) of hydro-alcohol extract, fractions and sub-fractions at the end of each phase of the process? Yeah? ,Huh? B? ,Huh? C? Is it? Yeah? ;f. monitoring of in vitro antioxidant activity (e24-e29) at the end of each process phase? Yeah? ,Huh? B? ,Huh? C? Is it? d. the multifunctional assets, obtained from the process described, can be applied in nutraceutic and/or functional foods, in formulations for combating anti-inflammatory activity, high pressure, hyperglycaemia, hyperlipidaemia and digestive problems, as well as used in the fight against aging.processo de extração, fracionamento e isolamento bioguiado de substâncias antioxidantes presentes nas folhas de moringa oleífera refere-se ao processo de extração, purificação e isolamento bioguiado de substâncias com elevado potencial antioxidante presente nas folhas de m. oleifera, sendo constituído das fases de: a. obtenção do extrato hidroalcoólico (e1- e5); b. fracionamento do extrato hidroalcoólico obtido (e6- e9); c. purificação em sílica gel (e10 ? e16); d. isolamento e identificação dos compostos ativos (e17- e20); e. monitoramento do perfil cromatográfico (e21- e23) do extrato hidroalcoólico, das frações e das subfrações ao final de cada fase do processo ?a?, ?b?, ?c? e ?d?; f. monitoramento da atividade antioxidante in vitro (e24- e29) ao final de cada fase do processo ?a?, ?b?, ?c? e ?d?. os ativos com caráter multifuncional, obtidos a partir do processo descrito, pod
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