Alternatives to pyridine derivatives containing ef2k inhibitors have vps34 inhibitor activity； drug synthesis containing these components； used in the treatment of CCER, depression, memory disorders and learning disorders

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专利权人:

JANSSEN PHARMACEUTICA N.V.

发明人:

DIELS, Gaston, Stanislas, Marcella,SCHOENTJES, Bruno,VERSELE, Matthias, Luc, Aimé,BERTHELOT, Didier, Jean-Claude,WILLEMS, Marc,VIELLEVOYE, Marcel,EMBRECHTS, Werner, Constant, Johan,WROBLOWSKI, Berthol

申请号：

CL2016002461

公开号：

CL2016002461A1

申请日:

2016.09.29

申请国别(地区):

CL

年份:

2017

代理人:

摘要：

wherein the variables have the meaning defined in the claims. The compounds according to the present invention have EF2K inhibitory activity and optionally also Vps34 inhibitory activity. The invention further relates to processes for preparing such novel compounds, pharmaceutical compositions comprising said compounds as an active ingredient as well as the use of said compounds as a medicament.COMPUESTOS DERIVADOS DE PIRIMIDINA CON ACTIVIDAD INHIBIDORA DE EF2K Y OPCIONALMENTE PRESENTAN ACTIVIDAD INHIBIDORA DE VPS34； COMPOSICIÓN FARMACÉUTICA QUE LOS COMPRENDE； USO EN EL TRATAMIENTO DEL CÁNCER, DEPRESIÓN, TRASTORNOS DE MEMORIA Y APRENDIZAJE

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/