Substituted Oxazol derivatives, such as strong selective inhibitors of FLT-3 and/or Syk inhibitors； synthesis of pharmaceuticals containing these substances； and those used to treat hematological malignancies, fear-spread disorders, other diffusion disorders, and autoimmune disorders Someone else.
The present invention is concerned with substituted azole derivatives that selectively modulate, regulate, and/or inhibit signal transduction mediated by certain native and/or mutant proteine kinases implicated in a variety of human and animal diseases such as cell proliferative, metabolic, allergic, and degenerative disorders. In particular, several of these compounds are potent and selective Flt-3 inhibitors or/and syk inhibitors.COMPUESTOS DERIVADOS DE OXAZOL SUSTITUIDOS, COMO INHIBIDORES POTENTES Y SELECTIVOS DE FLT-3 Y/O INHIBIDORES DE SYK； COMPOSICION FARMACEUTICA QUE LOS COMPRENDE； Y USO EN EL TRATAMIENTO DE LAS MALIGNIDADES HEMATOLOGICAS, TRASTORNO MIELOPROLIFERATIVO, OTROS TRASTORNOS PROLIFERATIVOS, AUTOINMUNES, ENTRE OTROS.
