process for the preparation of (2- (4- (2- (1-isopropyl-3-methyl-1h-1,2,4-triazol-5-yl) -5,6-dihydrobenzo [f] imidazo [1, 2-d] [1,4] oxazepin-9-yl) -1h-pyrazol-1-yl) -2-methylpropanamide (i) and compound
DANIAL R. BEAUDRY,DIANE E. CARRERA,FREDERIC ST-JEAN,REMY ANGELAUD,SUSHANT MALHOTRA,TRAVIS REMARCHUK
申请号：
BR112015020716
公开号：
BR112015020716A2
申请日:
2014.03.12
申请国别(地区):
BR
年份:
2017
代理人:
摘要：
summary “process for the preparation of (2- (4- (2- (1-isopropyl-3-methyl-1h-1,2,4-triazol-5-yl) -5,6-dihydrobenzo [f] imidazo [ 1,2-d] [1,4] oxazepin-9-yl) -1h-pyrazol-1-yl) -2-methylpropanamide (i) and compound ”The present invention relates to processes for preparing the pi3k inhibitor gdc-0032, formula i, which has the structure (gdc-0032), and the intermediates useful for the preparation of (i).resumo “processo para a preparação de (2-(4-(2-(1-isopropil-3-metil-1h-1,2,4-triazol-5-il)-5,6-diidrobenzo[f]imidazo[1,2-d][1,4]oxazepin-9-il)-1h-pirazol-1-il)-2-metilpropanamida (i) e composto” a presente invenção se refere aos processos para a preparação do inibidor de pi3k, gdc-0032, fórmula i, que possui a estrutura (gdc-0032), e os intermediários úteis para a preparação de (i).
