cysteamine in the treatment of fibrotic disease

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专利权人:

SEATTLE CHILDREN'S RESEARCH INSTITUTE

发明人:

ALLISON A. EDDY,DARYL M. OKAMURA

申请号：

BR112014009789

公开号：

BR112014009789A2

申请日:

2011.10.26

申请国别(地区):

BR

年份:

2017

代理人:

摘要：

Fibrotic diseases are characterized by the replacement of healthy tissue with scar tissue and extracellular matrix in response to tissue damage. Here we describe the reduction of extracellular matrix (ECM) deposition, interstitial fibroblasts, interstitial volume, expression of Collagen I mRNA and protein, expression of profibrotic cytokines and macrophage infiltration by Cysteamine treatment.

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中国工程科技知识中心

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