The Regents Of The University Of Colorado; a body corporate
发明人:
Thomas LAROCCA,Douglas SEALS
申请号：
US16875440
公开号：
US20200276203A1
申请日:
2020.05.15
申请国别(地区):
US
年份:
2020
代理人:
摘要：
Provided are methods for treating a disease or condition associated with reduced autophagy in a patient, which includes administering to the patient, either simultaneously or sequentially, a therapeutically effective amount of a synergistic combination of compounds from at least two and preferably three of the classes of compounds selected from a saccharide, a vitamin, a ketone body, a polyphenol, and a methylxanthine. The compounds may be present in a subtherapeutic effective amount relative to the compound's dosing when given as a single agent. Also provided are pharmaceutically acceptable compositions and kits including at least two and preferably three of the named classes of compounds.
