YAEL COHEN,LIVNAT BANGIO,ANDREW J. BRENNER,EYAL BREITBART
申请号：
US13826303
公开号：
US20130303595A1
申请日:
2013.03.14
申请国别(地区):
US
年份:
2013
代理人:
摘要：
Methods of treating a malignant glioma in a subject are disclosed. The methods comprise administering to the subject a therapeutically effective amount of a viral vector comprising: (i) a first polynucleotide sequence encoding a Fas-chimera (Fas-c), said first polynucleotide sequence comprising SEQ ID NOs: 2 and 3； and (ii) a second polynucleotide sequence encoding an endothelial cell-specific promoter or a periendothelial cell-specific promoter.
