Andrew J. Brenner;Livnat Bangio;Eyal Breitbart;Yael Cohen
发明人:
Yael Cohen,Livnat Bangio,Andrew J. Brenner,Eyal Breitbart
申请号：
US13520452
公开号：
US20130209450A1
申请日:
2011.01.05
申请国别(地区):
US
年份:
2013
代理人:
摘要：
Methods of treating a malignant glioma in a subject are disclosed. The methods comprise administering to the subject a therapeutically effective amount of a viral vector comprising: (i) a first polynucleotide sequence encoding a Fas-chimera (Fas-c), said first polynucleotide sequence comprising SEQ ID NOs: 2 and 3； and (ii) a second polynucleotide sequence encoding an endothelial cell-specific promoter or a periendothelial cell-specific promoter.
