National University Corporation Kumamoto University
发明人:
ERA Takumi,KIBOKU, Takayuki
申请号:
EP16866386
公开号:
EP3378490A4
申请日:
2016.11.17
申请国别(地区):
EP
年份:
2019
代理人:
摘要:
A pathological mechanism in FOP patients is further revealed, and development of a novel therapeutic drug, therapeutic method, diagnostic method, etc. utilizing an obtained finding is provided. The inventors have found a novel finding that in FOP, ectopic ossification, which occurs by an inflammation due to an injury, etc., is mediated by PARI to occur. From this finding, the inventors completed the present invention relating to a drug, etc. characterized by suppressing ectopic ossification in FOP by inhibiting PARI.