Ryan HUDSON;Melissa FLEURY;Roland GENDRON;Cameron SMITH;Adam D. HUGHES
发明人:
Cameron SMITH,Melissa FLEURY,Roland GENDRON,Ryan HUDSON,Adam D. HUGHES
申请号：
US13325453
公开号：
US20120157386A1
申请日:
2011.12.14
申请国别(地区):
US
年份:
2012
代理人:
摘要：
In one aspect, the invention relates to compounds having the formula:where R1-R6, a, b, and X are as defined in the specification, or a pharmaceutically acceptable salt thereof. These compounds have neprilysin inhibition activity. In another aspect, the invention relates to pharmaceutical compositions comprising such compounds； methods of using such compounds； and processes and intermediates for preparing such compounds.
