AGENTS DE MODULATION D'ATX

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专利权人:

BIOGEN MA INC.

发明人:

GUCKIAN, KEVIN,KUMARAVEL, GNANASAMBANDAM,MA, BIN,MI, SHA,PENG, HAIRUO,SHAO, ZHAOHUI,SUN, LIHONG,TAVERAS, ARTHUR,WANG, DEPING,XIN, ZHILI,ZHANG, LEI

申请号：

EP13822655

公开号：

EP2877166A4

申请日:

2013.07.26

申请国别(地区):

EP

年份:

2015

代理人:

摘要：

Disclosed are bicyclic aryl compounds of formula (I), that can modulate the activity of the autotaxin (ATX) enzyme. This invention further relates to compounds that are ATX inhibitors, and methods of making and using such compounds in the treatment of demyelination due to injury or disease, as well as for treating proliferative disorders such as cancer.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/