Mi Sha,Guckian Kevin,Kumaravel Gnanasambandam,Wang Deping,Ma Bin,Peng Hairuo,Shao Zhaohui,Sun Lihong,Taveras Arthur,Xin Zhili,Zhang Lei
申请号:
NZ70385213
公开号:
NZ703852A
申请日:
2013.07.26
申请国别(地区):
NZ
年份:
2018
代理人:
摘要:
Disclosed are bicyclic aryl compounds of formula (III), that can modulate the activity of the autotaxin (ATX) enzyme. This invention further relates to compounds that are ATX inhibitors, and methods of making and using such compounds in the treatment of demyelination due to injury or disease, as well as for treating proliferative disorders such as cancer.