Kevin M. Guckian,Gnanasambandam Kumaravel,Bin Ma,Sha Mi,Hairuo Peng,Zhaohui Shao,Lihong Sun,Arthur G. Taveras,Deping Wang,Zhili Xin,Lei Zhang
申请号：
US15296601
公开号：
US10017506B2
申请日:
2016.10.18
申请国别(地区):
US
年份:
2018
代理人:
摘要：
Disclosed are bicyclic aryl compounds of formula (I), that can modulate the activity of the autotaxin (ATX) enzyme. This invention further relates to compounds that are ATX inhibitors, and methods of making and using such compounds in the treatment of demyelination due to injury or disease, as well as for treating proliferative disorders such as cancer.
