The invention relates to triacyclic derivatives inhibitor, and the preparation method and application thereof. In particular, the present invention relates to compounds shown in general formula (I), their preparation methods and pharmaceutical compositions containing the compounds, and their use as phosphoinositide 3-kinase (PI3K) inhibitors in the treatment of cancer and diseases mediated or dependent on PI3K disorders.本發明涉及一種含三并環類衍生物抑制劑、其製備方法和應用。特別地,涉及通式(I)所示的化合物、其製備方法及含有該化合物的醫藥組成物,及其作為磷酸肌醇3激酶(PI3K)抑制劑,在治療癌症及介導或依賴於PI3K失調的疾病或病症的用途。