PROCÉDÉS ET COMPOSITIONS PERMETTANT L'OBTENTION DE VIRUS DE LA DENGUE RECOMBINÉS POUR LE DÉVELOPPEMENT DE VACCINS ET D'OUTILS DE DIAGNOSTIC

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专利权人:

The University of North Carolina at Chapel Hill

发明人:

申请号：

EP15854399.1

公开号：

EP3212672A4

申请日:

2015.11.02

申请国别(地区):

EP

年份:

2018

代理人:

摘要：

The present invention provides compositions and methods of use comprising a chimeric dengue virus E glycoprotein comprising a dengue virus E glycoprotein backbone, which comprises amino acid substitutions that introduce an epitope that is recognized by an antibody from a dengue virus serotype that is different from the dengue virus serotype of the dengue virus E glycoprotein backbone.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/