PROCEDES ET COMPOSITIONS PERMETTANT L'OBTENTION DE VIRUS DE LA DENGUE RECOMBINES POUR LE DEVELOPPEMENT DE VACCINS ET D'OUTILS DE DIAGNOSTIC

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专利权人:

THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL

发明人:

BARIC, RALPH,WIDMAN, DOUGLAS,YOUNT, BOYD,GALLICHOTTE, EMILY,ROYAL, SCOTT,DESILVA, ARAVINDA,SWANSTROM, JESICA

申请号：

CA2966198

公开号：

CA2966198A1

申请日:

2015.11.02

申请国别(地区):

CA

年份:

2016

代理人:

摘要：

The present invention provides compositions and methods of use comprising a chimeric dengue virus E glycoprotein comprising a dengue virus E glycoprotein backbone, which comprises amino acid substitutions that introduce an epitope that is recognized by an antibody from a dengue virus serotype that is different from the dengue virus serotype of the dengue virus E glycoprotein backbone.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/