The present invention provides aLactobacillus fermentumGKF3, a composition containing the same and its use for improving psychataxia by way of increasing the level of dopamine or/and serotonin in brain tissues.本發明提供一種發酵乳桿菌GKF3、含其之組合物及其改善精神失調之用途,藉由提升腦組織中多巴胺及/或血清素的含量以改善精神失調。