COTE DES COMBES SYLVAIN,코트-데-콩베, 실뱅,FROISSANT JACQUES,프루아상, 자크,GIBERT JEAN FRANCOIS,지베르, 장-프랑수아,MARGUET FRANK,마르그, 프랑크,PACAUD CHRISTOPHE,파코, 크리스토프,PUECH FREDERIC,프슈, 프레데리크,RAVET ANTOINE,라베, 앙투안
申请号：
KR1020127031424
公开号：
KR1020130113928A
申请日:
2011.06.01
申请国别(地区):
KR
年份:
2013
代理人:
摘要：
Compounds corresponding to the general formula (I) wherein R2 represents a group C1-10-alkyl, C3-10-cycloalkyl, C3-7-cycloalkyl-C1-6-alkyl, C1-6-alkyl-C3-7-cycloalkyl, C3-7-cycloalkyl-C3-7-cycloalkyl, C1-6-alkylthio-C-1-10-alkyl, C1-6-alkoxy-C1-10-alkyl, hydroxy-C1-10-alkyl, hydroxy-C1-6-alkyl-C3-7-cycloalkyl-C1-6-alkyl, hydroxy-C3-10-cycloalkyl, C1-10-fluoroalkyl or C3-10-fluorocycloalkyl； an optionally substituted heterocyclic group； a group C1-10-alkyl substituted with an optionally substituted heterocyclic group； X6 represents a group chosen from hydrogen, fluorine, chlorine and bromine atoms or a group C1-6-alkyl, C3-7-cycloalkyl, C3-7-cycloalkyl-C1-6-alkyl, C1-6-fluoroalkyl or cyano； and R7 represents an aryl group such as phenyl or naphthyl, optionally substituted with one or more substituents, in the form of the base or of an acid-addition salt, and the therapeutic use thereof.R2가 기 C1-10-알킬, C3-10-시클로알킬, C3-7-시클로알킬-C1-6-알킬, C1-6-알킬-C3-7-시클로알킬, C3-7-시클로알킬-C3-7-시클로알킬, C1-6-알킬티오-C-1-10-알킬, C1-6-알콕시-C1-10-알킬, 히드록시-C1-10-알킬, 히드록시-C1-6-알킬-C3-7-시클로알킬-C1-6-알킬, 히드록시-C3-10-시클로알킬, C1-10-플루오로알킬 또는 C3-10-플루오로시클로알킬； 임의로 치환된 헤테로시클릭 기； 임의로 치환된 헤테로시클릭 기로 치환된 기 C1-10-알킬을 나타내고； X6이 수소, 플루오린, 염소 및 브로민 원자, 또는 기 C1-6-알킬, C3-7-시클로알킬, C3-7-시클로알킬-C1-6-알킬, C1-6-플루오로알킬 또는 시아노로부터 선택된 기를 나타내고； R7이 1개 이상의 치환기로 임의로 치환된 아릴 기, 예컨대 페닐 또는 나프틸을 나타내는 것인, 염기 형태 또는 산 부가염 형태의 화학식 I에 상응하는 화합물. 치료 용도.
