Sylvain Cote Des Combes,Jacques Froissant,Jean-Francois Gibert,Frank Marguet,Christophe Pacaud,Frédéric Puech,Antoine Ravet
申请号：
US13688916
公开号：
US08791119B2
申请日:
2012.11.29
申请国别(地区):
US
年份:
2014
代理人:
摘要：
Compounds corresponding to the general formula (I)wherein R2 represents a group C1-10-alkyl, C3-10-cycloalkyl, C3-7-cycloalkyl-C1-6-alkyl, C1-6-alkyl-C3-7-cycloalkyl, C3-7-cycloalkyl-C3-7-cycloalkyl, C1-6-alkylthio-C-1-10-alkyl, C1-6-alkoxy-C1-10-alkyl, hydroxy-C1-10-alkyl, hydroxy-C1-6-alkyl-C3-7-cycloalkyl-C1-6-alkyl, hydroxy-C3-10-cycloalkyl, C1-10-fluoroalkyl or C3-10-fluorocycloalkyl； an optionally substituted heterocyclic group； a group C1-10-alkyl substituted with an optionally substituted heterocyclic group； X6 represents a group chosen from hydrogen, fluorine, chlorine and bromine atoms or a group C1-6-alkyl, C3-7-cycloalkyl, C3-7-cycloalkyl-C1-6-alkyl, C1-6-fluoroalkyl or cyano； and R7 represents an aryl group such as phenyl or naphthyl, optionally substituted with one or more substituents,in the form of the base or of an acid-addition salt, and the therapeutic use thereof.
