HORNE WILLIAM S U S A,GELLMAN SAMUEL H U S A,JOHNSON LISA M U S A
申请号：
IN3295/DELNP/2011
公开号：
IN300183B
申请日:
2009.10.14
申请国别(地区):
IN
年份:
2018
代理人:
摘要：
Described is a method of fabricating biologically active, unnatural polypeptides. The method includes the steps of selecting a biologically active polypeptide or biologically active fragment thereof having an amino acid sequence comprising a-amino acid residues, and fabricating a synthetic polypeptide that has an amino acid sequence that corresponds to the sequence of the biologically active polypeptide, but wherein about 14% to about 50% of the a-amino acid residues found in the biologically active polypeptide or fragment of step (a) are replaced with ß-amino acid residues, and the a- amino acid residues are distributed in a repeating pattern. WO2010045342A1
