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EXPRESSION SYSTEM OF RECOMBINANT PROTEINS WITH ENHANCED YIELD AND IMMUNOGENICITY
专利权人:
发明人:
申请号:
EP08748503.3
公开号:
EP2154251B1
申请日:
2008.05.15
申请国别(地区):
EP
年份:
2013
代理人:
摘要:
An expression system for a recombinant target protein in a host cell, comprising a nucleic acid segment consisting essentially of a nucleotide sequence coding for a protein transduction domain of SEQ ID No: 1, a nucleotide sequence coding for a Hsp40-J domain, and a nucleotide sequence coding for a target protein, wherein the nucleic acid segment is operatively linked to host specific transcription and translation regulatory elements for expressing the recombinant target protein in the host cell is provided. The invention also provides a method for producing a recombinant target protein with an enhanced yield in the host cell.
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