John Dick;Jean C.Y. Wang;Liqing Jin;Alexandre Theocharides;Sujeetha Rajakumar;Jayne Danska
发明人:
Jean C.Y. Wang,John Dick,Jayne Danska,Liqing Jin,Alexandre Theocharides,Sujeetha Rajakumar
申请号:
US13320629
公开号:
US20120189625A1
申请日:
2010.05.14
申请国别(地区):
US
年份:
2012
代理人:
摘要:
The invention relates to modulating the SIRPα-CD47 interaction in order to treat hematological cancer and compounds therefor. In some embodiments, there is provided methods and uses of SIRPα polypeptides, fragments and fusion proteins for treating hematological cancer, preferably human acute myeloid leukemia.