UNIVERSITY HEALTH NETWORK;THE HOSPITAL FOR SICK CHILDREN
发明人:
Wang, C. Y. Jean,Dick, John,Danska, Jayne,Jin, Liqing,Rajakumar, Sujeetha,Theocharides, Alexandre
申请号:
AU2018256470
公开号:
AU2018256470A1
申请日:
2018.10.29
申请国别(地区):
AU
年份:
2018
代理人:
摘要:
The invention relates to modulating the SIRPa-CD47 interaction in order to treat hematological cancer and compounds therefor. In some embodiments, there is provided methods and uses of SIRPa polypeptides, fragments and fusion proteins for treating hematological cancer, preferably human acute myeloid leukemia.