University Health Network;The Hospital for Sick Children
发明人:
Wang, C. Y. Jean,Dick, John,Danska, Jayne,Jin, Liqing,Rajakumar, Sujeetha,Theocharides, Alexandre
申请号:
AU2020220183
公开号:
AU2020220183A1
申请日:
2020.08.21
申请国别(地区):
AU
年份:
2020
代理人:
摘要:
#$%^&*AU2020220183A120200910.pdf#####ABSTRACT: The invention relates to modulating the SIRPa - CD47 interaction in order to treat hematological cancer and compounds therefor. In some embodiments, there is provided 5 methods and uses of SIRPa polypeptides, fragments and fusion proteins for treating hematological cancer, preferably human acute myeloid leukemia.