The present invention relates to arylthiazine compounds, metabolites, N-oxides, amides, esters, pharmaceutically acceptable salts, hydrates and solvates thereof and their use as cytoprotectants in the treatment or prophylaxis of diseases or states, either acute or chronic, involving aberrant cellular lipid peroxidation in the central nervous system or in the periphery of the body. The present invention also relates to a method for their preparation and to pharmaceutical composition comprising as an active ingredient one or more of the aforementioned compounds.本發明係相關於芳基噻嗪化合物、其代謝物、N氧化物、醯胺、酯類、醫藥上可接受的鹽類、水合物、溶劑化物，以及其作為中樞神經系統或身體周邊的急性或慢性，涉及異常細胞脂質過氧化作用的疾病或狀態之治療或預防的細胞保護劑之用途。本發明亦相關於它們的製備方法，以及相關於包含一或更多前述化合物作為活性成分的醫藥組成物。
