JAEN, JUAN CARLOS,JEFFREY, JENNA LEIGH,JIN, LIXIA,KALISIAK, JAROSLAW,LAWSON, KENNETH V.,LELETI, MANMOHAN REDDY,KARAKUNNEL, JOYSON J.,POWERS, JAY PATRICK
申请号：
CA3092585
公开号：
CA3092585A1
申请日:
2019.03.08
申请国别(地区):
CA
年份:
2019
代理人:
摘要：
Methods of identifying compounds that modulate the conversion of AMP to adenosine by 5'-nucleotidase, ecto, and that possess particular pharmacokinetic characteristics are described herein. Methods of such compounds, and compositions comprising same, for the treatment and/or prevention of a diverse array of diseases, disorders and conditions, including cancer- and immune-related disorders, are also provided.
