Sourena Nadji,James T. Smoot,Joseph A. Vanartsdalen
申请号：
US14256235
公开号：
US09255119B2
申请日:
2014.04.18
申请国别(地区):
US
年份:
2016
代理人:
摘要：
Processes for the synthesis of the Factor Xa anticoagulent Fondaparinux, and related compounds are described. Also described are protected pentasaccharide intermediates as well as efficient and scalable processes for the industrial scale production of Fondaparinux sodium by conversion of the protected pentasaccharide intermediates via a sequence of deprotection and sulfonation reactions.
