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Angiotensin II receptor antagonists
专利权人:
Silvia Stefanini;Ennio Ongini;Iyassu K. Sebhat;Stefano Biondi;Nicoletta Almirante;Michael Man-Chu Lo;Amjad Ali;Christopher Franklin
发明人:
Amjad Ali,Michael Man-Chu Lo,Christopher Franklin,Iyassu K. Sebhat,Nicoletta Almirante,Silvia Stefanini,Stefano Biondi,Ennio Ongini
申请号:
US13483213
公开号:
US08367711B2
申请日:
2012.05.30
申请国别(地区):
US
年份:
2013
代理人:
摘要:
A compound having the structure wherein R is, for example, Y is selected from the group consisting of 1) R5, 2) —C(R1R2) (C(R3R4))0-1Y1R5, and 3) —C(R1R2)—O—Y1R5; R1, R2, R3 and R4 are independently selected from the group consisting of hydrogen and C1-4 alkyl; R5 is; Y1 is selected from the group consisting of C(O)—O— and P(O)(OR6)—O—; and R6 is hydrogen or CH3, or a pharmaceutically acceptable salt thereof, and methods of using the compounds for treating hypertension.
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