Using truncated guide RNAs (tru-gRNAs) to increase specificity for RNA-guided genome editing
- 专利权人:
- 发明人:
- J. Keith Joung,Jeffry D. Sander,Morgan Maeder,Yanfang Fu
- 申请号:
- US14213723
- 公开号:
- US09567604B2
- 申请日:
- 2014.03.14
- 申请国别(地区):
- US
- 年份:
- 2017
- 代理人:
- 摘要:
- Methods for increasing specificity of RNA-guided genome editing, e.g., editing using CRISPR/Cas9 systems, using truncated guide RNAs (tru-gRNAs).
- 来源网站:
- 中国工程科技知识中心
相关发明人
相关专利
- Increasing specificity for RNA-guided genome editing
- Using RNA-guided foki nucleases (RFNs) to increase specificity for RNA-guided genome editing
- USING RNA-GUIDED FOKI NUCLEASES (RFNS) TO INCREASE SPECIFICITY FOR RNA-GUIDED GENOME EDITING
- NUCLEASES SPECIFIQUES DE SITE A REGULATION EPIGENETIQUE
- 一种用于猪基因编辑的高效特异性sgRNA识别位点引导序列及其筛选方法