NUCLEASES SPECIFIQUES DE SITE A REGULATION EPIGENETIQUE

• 收藏
• 分享

专利权人:

THE GENERAL HOSPITAL CORPORATION

发明人:

JOUNG, J. KEITH,GEHRKE, JASON MICHAEL

申请号：

CA3040481

公开号：

CA3040481A1

申请日:

2017.10.16

申请国别(地区):

CA

年份:

2018

代理人:

摘要：

Methods and compositions for improving the specificity of genome-editing nucleases (e.g., RNA-guided CRISPR-Cas nucleases or engineered zinc finger nucleases) and customizable DNA-binding domain fusion proteins (e.g., RNA-guided dead-Cas9, RNA-guided dead-Cpf1, or engineered zinc finger arrays fused to transcriptional regulatory domains) for use as research reagents, in gene drives, or as therapeutic agents.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/