VERFAHREN ZUR HERSTELLUNG VON MIT EINEM HYDROPHILEN MATERIAL BESCHICHTETEN EISENOXIDNANOPARTIKELN UND KONTRASTMITTEL FÜR DIE MAGNETRESONANZTOMOGRAPHIE DAMIT

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专利权人:

HANWHA CHEMICAL CORPORATION

发明人:

HYEON, TAEGHWAN,PIAO, YUANZHE,PARK, YONG IL

申请号：

EP12744201

公开号：

EP2673006A4

申请日:

2012.02.06

申请国别(地区):

EP

年份:

2016

代理人:

摘要：

The present invention relates to a method of preparing biocompatible iron oxide nanoparticles by coating iron oxide nanoparticles having improved magnetism via annealing treatment using salt particles with a hydrophilic material and to a magnetic resonance imaging (MRI) contrast agent including the iron oxide nanoparticles prepared thereby. Among hydrophilic materials, carboxymethyl dextran (CM-dextran) is the most efficient in terms of stabilizing the annealed iron oxide nanoparticles and exhibiting contrast effects.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/