HUBBELL, JEFFREY, A.,O'NEIL, CONLIN, P.,REDDY, SAI, T.,SWARTZ, MELODY, A.,VELLUTO, DIANA,VAN DER VLIES, ANDRE,SIMEONI, ELEONORA,ONEIL, CONLIN, P.
申请号：
EP09810632
公开号：
EP2341897A4
申请日:
2009.08.28
申请国别(地区):
EP
年份:
2013
代理人:
摘要：
Nanoparticles that activate complement in the absence of biological molecules are described. The nanoparticles are shown to specifically target antigen presenting cells in specifically in lymph nodes, without the use of a biological molecule for targeting. These particles are useful vehicles for delivering immunotherapeutics. Surface chemistries and chemical formulations for the nanoparticles are described.
