HUBBELL, JEFFREY A.,O'NEIL, CONLIN P.,REDDY, SAI T.,SWARTZ, MELODY A.,VELLUTO, DIANA,VAN DER VLIES, ANDRE,SIMEONI, ELEONORA
申请号:
CA2735318
公开号:
CA2735318C
申请日:
2009.08.28
申请国别(地区):
CA
年份:
2017
代理人:
摘要:
Nanoparticles that activate complement in the absence of biological moleculesare described. The nanoparticles areshown to specifically target antigen presenting cells in specifically in lymphnodes, without the use of a biological molecule fortargeting. These particles are useful vehicles for deliveringimmunotherapeutics. Surface chemistries and chemical formulationsfor the nanoparticles are described.