CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS)
发明人:
MEIJER, LAURENT,SKALTSOUNIS, LEANDROS,MIKROS, EMMANUEL,MAGIATIS, PROKOPIOS,JOHNSON, CARL
申请号：
CA2732232
公开号：
CA2732232C
申请日:
2009.07.21
申请国别(地区):
CA
年份:
2017
代理人:
摘要：
Indirubin derivatives of formula (I) wherein R represents -(A)n-R1 or -CO-N(R2,R3) with .cndot. A being C1-C5 alkylenegroup, optionally substituted by one or several A1 radical, A1 being anhalogen Br, OH, OR' or NH2, R4 being C1-C5 alkyl； -R1 being halogen, OH, N(R2, R3)； R2 and R3, identical or different, being C1-C5 alkyl, optionally substituted by A1 such as abovedefined, or R2 and R3 are part of a cycle with 5 or 6 elements optionallycomprising another heteroatom such as O or N； .cndot. n = 1-5.It also relates to the biological application thereof.
