JOHN EDGAR DICK,LIQING JIN,GINO LUIGI VAIRO,DAVID PAUL GEARING,SAMANTHA JANE BUSFIELD
申请号：
US14552789
公开号：
US20150152185A1
申请日:
2014.11.25
申请国别(地区):
US
年份:
2015
代理人:
摘要：
A method for inhibition of leukemic stem cells expressing IL-3R.alpha. (CD 123), comprises contacting the cells with an antigen binding molecule comprising a Fc region or a modified Fc region having enhanced Fc effector function, wherein the antigen binding molecule binds selectively to IL-3R.alpha. (CD123). The invention includes the treatment of a hematologic cancer condition in a patient by administration to the patient of an effective amount of the antigen binding molecule.
