TSAI, Chun-che,McGUIRE, Karen, M.,JAMISON, James, M.,SUMMERS, Jack, L.
申请号:
SG11201707919Q
公开号:
SG11201707919QA
申请日:
2016.04.07
申请国别(地区):
SG
年份:
2017
代理人:
摘要:
R1 to R4 are independent substituents at any available position of the phenyl rings, preferably at 3, 3′, 4, 4′, and/or 5, 5′; and m, n, p, and q are independently 0, 1, 2, or 3 representing the number of substituents of the rings, respectively, but at least one of m or n must be ≥1. Each R1 to R2 is independently selected from substituents described herein, including but not limited to hydroxyl, alkoxy, halo, halomethyl and glycosides. The formulation may also include an auxiliary autophagy modulating compound (AAM) as described herein. The formulation may include a hydrogel formed by the compounds themselves or otherwise and may include salts and/or complexes.