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Crystal Forms of Saxagliptin and Processes for Preparing Same
专利权人:
Bristol-Myers Squibb Company
发明人:
Jack Z. Gougoutas,Mary F. Malley,John D. DiMarco,Xiaotian S. Yin,Chenkou Wei,Jurong Yu,Truc Chi Vu,Gregory Scott Jones,Scott A. Savage
申请号:
US14142081
公开号:
US20140121155A1
申请日:
2013.12.27
申请国别(地区):
US
年份:
2014
代理人:
摘要:
Physical crystal structures of a compound of the formula I:are provided including the free base monohydrate thereof (form H-1) and the hydrochloric acid salt thereof, including hydrochloric acid salt containing 0.75 equivalent of H2O (form H0.75-3) and hydrochloric acid salt containing 2 equivalents of H2O (form H2-1), and hydrochloric acid salt Pattern P-5, preferably in substantially pure form, and other forms as described herein, pharmaceutical compositions containing structures of compound I or IA, processes for preparing same, intermediates used in preparing same, and methods of treating diseases such as diabetes using such structures.
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中国工程科技知识中心
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