Blaise N'Zemba;Regis Leung-Toung;Yanqing Zhao;Lily Yu;Tim Fat Tam;Yingsheng Wang
发明人:
Tim Fat Tam,Blaise N'Zemba,Regis Leung-Toung,Yingsheng Wang,Yanqing Zhao,Lily Yu,Blaise NZemba
申请号:
US12520337
公开号:
US08138221B2
申请日:
2007.12.13
申请国别(地区):
US
年份:
2012
代理人:
摘要:
The present invention relates to pharmaceutically acceptable crystalline and amorphous salts of D-isoglutamyl-D-tryptophan as well as processes for their manufacture, pharmaceutical compositions comprising them, and their uses in the preparation of pharmaceutical compositions for the treatment of various conditions and/or diseases. In particular, the present invention relates to D-isoglutamyl-D-tryptophan potassium salt (1:1), D-isoglutamyl-D-tryptophan lithium salt (1:1), D-isoglutamyl-D-tryptophan calcium salt (2:1), D-isoglutamyl-D-tryptophan magnesium salt (2:1), and D-isoglutamyl-D-tryptophan organic ammonium salts (1:1).