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Derivatives of exendin
专利权人:
发明人:
申请号:
EP10001237.6
公开号:
EP2223938B1
申请日:
2002.05.08
申请国别(地区):
EP
年份:
2013
代理人:
摘要:
The present invention relates to derivates of an insulinotropic peptide Exendin-4 and pharmaceutically acceptable salts produced thereof, which are useful for the treatment of type II diabetes. The derivate has the chemical structure as shown below:In which:X represents Leu, Y represents Lys and Z represents Arg-OH.The derivates of this invention may be prepared by synthetic chemical means, and more easily, by the recombinant techniques, which makes it possible to commercial production.
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