PROBLEM TO BE SOLVED: To reduce the cost of blood purification treatment by reducing burdens on a doctor and a nurse due to replacement of a purification liquid bag in the blood purification treatment over a long period of time.SOLUTION: A blood purification system A includes: a blood purification device 1 provided with a blood circuit 11 having a blood purifier 10 and a purification liquid circuit 12 for supplying blood purification liquid to the blood purifier 10 and discharging it a purification liquid generator 2 for generating the purification liquid a purification liquid replenishing circuit 3 for connecting the purification liquid generator 2 and the purification liquid circuit 12 in order to replenish the purification liquid generated in the purification liquid generator 2 to the purification liquid bag 50 of the purification liquid circuit 12 and a communication means 4 for performing communication of information between the blood purification device 1 and the purification liquid generator 2 so as to replenish the purification liquid of the purification liquid generator 2 to the purification liquid bag 50 through the purification liquid replenishing circuit 3 when the liquid amount of the purification liquid in the purification liquid bag 50 becomes equal to or smaller than a prescribed threshold.COPYRIGHT: (C)2013,JPO&INPIT【課題】長時間の血液浄化治療における浄化液バッグの交換による医師や看護師の負担を軽減し、血液浄化治療の低コスト化を実現する。【解決手段】血液浄化システムAは、血液浄化器10を有する血液回路11と、血液浄化器10に血液の浄化液を供給し排出する浄化液回路12と有する血液浄化装置1と、浄化液を生成する浄化液生成装置2と、浄化液生成装置2で生成された浄化液を、浄化液回路12の浄化液バッグ50に補充するために、浄化液生成装置2と浄化液回路12とを接続する浄化液補充回路3と、浄化液バッグ50の浄化液の液量が所定の閾値以下になったときに、浄化液生成装置2の浄化液が浄化液補充回路3を通じて浄化液バッグ50に補充されるように、血液浄化装置1と浄化液生成装置2との間で情報の通信を行う通信手段4と、を有する。【選択図】図1