GILLJAM, GUSTAV,JERNBERG, MATS,WINGE, STEFAN,NEISSER-SVAE, ANDREA
申请号：
CA2696865
公开号：
CA2696865C
申请日:
2008.08.25
申请国别(地区):
CA
年份:
2019
代理人:
摘要：
A process for isolation and purification of a target protein by chromatographywherein the chromatography removesor depletes prions (PrP sc), comprising the steps of contacting a potentiallyPrP sc contaminated sample comprising a target proteinwith a multimodal chromatographic material； setting buffer conditions so thatthe target protein is bound to the multimodalchro-matographic material and whereas PrP sc is not binding to the multimodalchromatographic material； followed by elution of the targetprotein.a process for isolation and purification of a target protein free ofprion protein (prp sc).
