PROCESS FOR THE INSULATION AND PURIFICATION OF A PRION PROTEIN FREE TARGET PROTEIN (PrPsc)

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专利权人:

OCTAPHARMA AG

发明人:

GUSTAV GILLJAM,MATS JERNBERG,STEFAN WINGE,ANDREA NEISSER-SVAE

申请号：

BRPI0815758

公开号：

BRPI0815758A2

申请日:

2008.08.25

申请国别(地区):

BR

年份:

2014

代理人:

摘要：

A process for isolation and purification of a target protein by chromatography comprising the steps of - contacting a potentially PrP SC -contaminated sample comprising a target protein with a multimodal chromatographic material； - setting buffer conditions so that the target protein is bound to the multimodal chromatographic material and PrP SC are eluted； followed by elution of the target protein.

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