The invention relates to 6-piperidinyl-substituted isoquinoline derivatives of the formula (I) useful for the treatment and/or prevention of diseases associated with Rho-kinase and/or Rho-kinase mediated phosphorylation of myosin light chain phosphatase, and compositions containing such compounds.本發明係關於具下式(I)之6-六氫吡啶基-經取代的異喹啉衍生物類;(I),;有用於供治療及/或預防與Rho-激酶有關聯的疾病及/或受Rho-激酶介導的肌球蛋白輕鏈磷酸酶(myosin light chain phosphatase)之磷酸化反應,以及含這類化合物之組成物。