LIU, CHUNJIAN,YANG, MICHAEL G.,XIAO, ZILI,CHEN, LING,MOSLIN, RYAN M.,TOKARSKI, JOHN S.,WEINSTEIN, DAVID S.,WROBLESKI, STEPHEN T.
申请号:
CA3083122
公开号:
CA3083122A1
申请日:
2018.11.19
申请国别(地区):
CA
年份:
2019
代理人:
摘要:
Compounds having the following formula (I), or a stereoisomer or pharmaceutically-acceptable salt thereof, where R1, R2, R3, R4, and R5 are as defined herein, are useful in the modulation of IL-12, IL-23 and/or IFNa, by acting on Tyk-2 to cause signal transduction inhibition.