Wayne R. Danter,Martyn Brown,George Ma,Ghenadie Rusu,Jianhua Zhong,Natalie Lazarowych,Stephen Houldsworth
申请号：
US12510862
公开号：
US08252800B2
申请日:
2009.07.28
申请国别(地区):
US
年份:
2012
代理人:
摘要：
The present invention relates to compounds of the Formula I, the pharmaceutically acceptable salts and stereoisomers thereof, which inhibit, regulate and/or modulate tyrosine kinase signal transduction, compositions which contain these compounds, and methods of using them to treat tyrosine kinase-dependent diseases and conditions in mammals:wherein n is an integer, preferably n is 1 wherein R1 and R2 are independently selected from the group consisting of:
