3′；-deamino-3′；-(2″；-pyrroline-1″；-yl)-5-imino-13-deoxyanthracyclines and methods of preparation

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专利权人:

Monopar Therapeutics Inc.

发明人:

Richard Olson,Gerald Walsh

申请号：

US15434617

公开号：

US10450340B2

申请日:

2017.02.16

申请国别(地区):

US

年份:

2019

代理人:

摘要：

2-pyrrolino-13-deoxyanthracycline derivatives, medical uses thereof, and a process for making them. A 2-pyrrolino-13-deoxyanthracycline and a 13-deoxyanthracycline can be administered to a patient simultaneously or sequentially in amounts to produce a synergistic therapeutic effect with increased potency and efficacy, compared to the sum of the effects of each drug when administered alone. A composition or preparation of a 2-pyrrolino-13-deoxyanthracycline and a 13-deoxyanthracycline for producing a potent anticancer therapeutic effect is also provided.

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中国工程科技知识中心

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http://www.ckcest.cn/home/