Oxazina derivatives and their application in the treatment of neurotoxicity

• 收藏
• 分享

专利权人:

NOVARTIS AG

发明人:

BADIGER SANGAMESH,CHEBROLO MRALI,FREDERIKSEN MATHIAS,HOLZER PHILIPP,HURTH KONSTANZE,LI LEI,LUI HUI,LUEOEND RAINER MARTIN,MACHAUER RAINER,MOEBITZ HENRIK,NEUMANN ULF,RAMOS RITA,RUEEGER HEINRICH,SCHAEFER

申请号：

CO12033027

公开号：

CO6501189A2

申请日:

2012.02.24

申请国别(地区):

CO

年份:

2012

代理人:

摘要：

Derivatives of the kernel (3 - (4 - amino - 2 - 3.6 - dihydro - 2H - 1.4 - oxazin - 3 - phenyl carboxamide or (IL) - 3 - (5 - amino - 3.6 - dihydro - 2 - 2H - 1.4 - oxazin - phenyl - 3 - il) carbotioamida, of formula (I) which present bace Inhibitory activity, in free form or in Salt, Methods for their Preparation and compositions farmac u00e9u Policies to contain it.Derivados del núcleo (3-(5-amino-3,6-dihidro-2-2H-1,4-oxazin-3-il)fenil-carboxamida o (3-(5-amino-3,6-dihidro-2-2H-1,4-oxazin-3-il)fenil-carbotioamida, de Fórmula (I)Los cuales presentan actividad inhibidora de BACE, en forma libre o de sal, métodos para su preparación y composiciones farmacéuticas que los contienen.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/