SUBSTITUTED 2-AZA-BICYCLO[2.2.1]HEPTANE-3-CARBOXYLIC ACID (CYANO-METHYL)-AMIDES INHIBITORS OF CATHEPSIN C

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专利权人:

Thorsten OOST;Alexander PAUTSCH;Marc GRUNDL;Gerd MORSCHHAEUSER;Ralf ANDERSKEWITZ

发明人:

Ralf ANDERSKEWITZ,Marc GRUNDL,Gerd MORSCHHAEUSER,Thorsten OOST,Alexander PAUTSCH

申请号：

US14205881

公开号：

US20140275114A1

申请日:

2014.03.12

申请国别(地区):

US

年份:

2014

代理人:

摘要：

This invention relates to 2-Aza-bicyclo[2.2.1]heptane-3-carboxylic acid (cyano-methyl)-amides of formula 1and their use as inhibitors of Cathepsin C, pharmaceutical compositions containing the same, and methods of using the same as agents for treatment and/or prevention of diseases connected with dipeptidyl peptidase I activity, e.g. respiratory diseases.

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