SUBSTITUTED 2-AZA-BICYCLO[2.2.1]HEPTANE-3-CARBOXYLIC ACID (BENZYL-CYANO-METHYL)-AMIDES INHIBITORS OF CATHEPSIN C

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专利权人:

BOEHRINGER INGELHEIM INTERNATIONAL GMBH

发明人:

ANDERSKEWITZ, RALF,GRAUERT, MATTHIAS,GRUNDL, MARC,HAEBEL, PETER, WILHELM,OOST, THORSTEN,PAUTSCH, ALEXANDER,PETERS, STEFAN,BINDER, FLORIAN,VINTONYAK, VIKTOR

申请号：

SG11201507382Q

公开号：

SG11201507382QA

申请日:

2014.03.12

申请国别(地区):

SG

年份:

2015

代理人:

摘要：

This invention relates to 2-Aza-bicyclo[2.2.1]heptane-3-carboxylic acid (benzyl-cyano-methyl)-amides of formula 1 and their use as inhibitors of Cathepsin C, pharmaceutical compositions containing the same, and methods of using the same as agents for treatment and/or prevention of diseases connected with dipeptidyl peptidase I activity, e.g. respiratory diseases.

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