The Trustees of Columbia University in the City of New York
发明人:
申请号:
EP10164397.1
公开号:
EP2292631B1
申请日:
2003.04.23
申请国别(地区):
EP
年份:
2017
代理人:
摘要:
This invention provides a method of treating a disorder of a subject's heart involving loss of cardiomyocytes which comprises administering to the subject an amount of an agent effective to cause cardiomyocyte proliferation within the subject's heart so as to thereby treat the disorder. This invention further provides the instant method wherein the agent is human endothelial progenitor cells, G-CSF, GM-CSF, SDF-1, and IL-8. This invention also provides methods of determining the susceptibility of a cardiomyocyte in a subject to apoptosis.